Though fire seemed to destroy the fungal structures, Tyki thinks that an end should be put to the leader of the Globsnaga Orcs.
'Burning fungus-infested structures may be a slow help, but it is not enough, I fear. To end the infestation, I believe we will have to cut the head from the serpent, so to speak.
'The leader of the Globsnaga Orcs can be found to the south at Dalgum-ru. I think his existence has been tolerated quite long enough.
'When the deed is done, return to me.'
The Globsnaga leader can be found at Dalgum-ru, south of the Shadowed Refuge.
Tyki wants you to find the Orc-leader at Dalgum-ru and put an end to his offending existence.
Tyki is at the Shadowed Refuge, north of Dalgum-ru.
You should return to Tyki to tell him of the death of Zarza, the Orc-leader.